WHAT IS METABOLAID®?
Metabolaid® is a branded ingredient based on hibiscus and lemon verbena extracts, a unique combination that can help individuals maintain a healthy weight and heart. Several clinical studies have shown that Metabolaid helps to:
- Maintain a healthy body weight and waistline
- Promote a healthy cholesterol profile
- Support a healthy blood pressure parameters
- Maintain healthy blood glucose parameters
Also, the sustained consumption of Metabolaid® has an effect in satiety, allowing you to control your appetite to maintain a healthy body weight.
Metabolaid® is the result of more than 7 years of scientificresearch in both animal models and clinical studies. This studies were performed in collaboration with renown experts from various Universities, Research Centers, and Hospitals. Only with great scientific rigor can such a high quality and efficient product be produced, as is the case of MetabolAid®.
MetabolAid® is a patent-protected ingredient based on propietary technology-based extracts from lemon verbena and hibiscus flower.
Metabolaid® activates the AMPK pathway, responsible for decreasing lipid accumulation in the adipose tissue and liver.
The major molecular components that comprise Metabolaid® are verbascoside (from the lemon verbena) and anthocyanins (from the hibiscus). This proprietary combination of components works synergistically, enhancing their effect more so than if they were taking individually. Metabolaid® acts upon various tissues (adipose tissue, liver and muscles) by activating AMPK, which is a master metabolic switch*. In the muscles, the phosphorylated form of AMPK activates mechanisms to increase glucose and fatty acid uptake from the bloodstream, due to increased mitochondrial biogenesis. In the adipose tissue, AMPK activation favors the use of fatty deposits and release fatty acids to the bloodstream, while decreasing lipogenesis and lipid storage, resulting in decreased triglyceride accumulation. In the liver, AMPK activation decreases glucose production and lipid accumulation, as well as increases lipid oxidation/degradation.
Overall, Metabolaid® activates AMPK, which favors the use of the body’s own energy reservoirs over other sources, making Metabolaid® an efficient "fat burner!
REFERENCE: Lee YS et al (2018). Metabolaid® Combination of Lemon Verbena and Hibiscus Flower Extract Prevents High-Fat Diet-Induced Obesity through AMP-Activated Protein Kinase Activation. Nutrients. 10(9). pii: E1204.
Several clinical studies have shown that 500mg of Metabolaid for 60 days*, when accompanied by a healthy diet and regular exercise, resulted in (compared to placebo-controlled group following the same diet and exercise regime):
Clinical studies have shown that Metabolaid helps consumers on diet to have a better control over their body weight, blood pressure, cholesterol, and glucose levels, more so than with diet alone! Consumers of Metabolaid reported losing twice as much body weight, and 4 times less waistline!*
REFERENCES: 1. Boix-Castejón M et al (2018). Hibiscus and lemon verbena polyphenols modulate appetite-related biomarkers in overweight subjects: a randomized controlled trial. Food Funct. 9(6):3173-3184. 2. Herranz-Lopez M et al (2019). Differential effects of a combination of Hibiscus sabdariffa and Lippia citriodora polyphenols with AMPK-activating capacity in overweight/obese subjects: A randomized controlled trial. Scientific Reports 9, Article number: 2999 (2019)
THE GUT-BRAIN AXIS
Appetite is controlled by an intricate combination of gut hormones from the digestive/endocrine systems (stomach, small and large intestine, adipose tissue, pancreas) which reach the hypothalamus of the brain to induce or suppress appetite. Several of the most relevant gut hormones include the hunger-inducing ghrelin from the stomach, satiety-inducing GLP-1 from the large intestine and satiety inducing leptin from the adipose tissue. In this sense, satiety-regulating hormones were analyzed in a clinical study where individuals underwent a diet and exercise regime*.
Ghrelin was shown to not be affected when taking Metabolaid, while the placebo group presented higher levels (therefore, feeling hungrier). As for GLP-1, a satiety-inducing hormone, this was increased in those taking Metabolaid. Overall, the results of the clinical studies indicated that individuals on a diet and exercise regime while taking the supplement reported fuller faster, and therefore ate less, which helped control their cravings and overall, help them maintain a healthy body weight.
Leptin is unique in that it is a satiety-inducing hormone, yet individuals that are overweight have high levels of leptin in blood. This is because they present leptin resistance, requiring higher concentrations of the hormone to induce a satiety effect. In the published clinical study, leptin was significantly decreased, indicating a possible correlation with increased leptin sensitivity/appetite suppression. Satiety was further assessed using validated perception questionnaires. As early as 15 days after taking Metabolaid, the volunteers following a diet and exercise regime noted to feel less hungry during the day, and more satisfied with the amount of food they ate. And the longer they took the product, the stronger the effect.
REFERENCE: Boix-Castejón M et al (2018). Hibiscus and lemon verbena polyphenols modulate appetite-related biomarkers in overweight subjects: a randomized controlled trial. Food Funct. 9(6):3173-3184.
Once the consumer purchase the product and downloads the app, the application will help them monitor their daily habits (eating hours and frequency, sleep) as well as allow the connection to other wearable devices to detect health-related parameters (heart rate, steps taken, body weight).
For example, Metabolaid is known to have a significant effect in controlling a consumer´s appetite. Therefore, the consumer will be able to detect changes in their diet (such as avoiding mid-meal snacks, or reduce food intake) even before they would otherwise notice if they did not use the mobile application.
Also, the app is designed to include behavioral, life style as part of the consumer's daily habits. This is important, as maintaining a healthy body weight and heart can only be achieved if a proper diet and regular exercise is included into the daily habits.
Therefore, the Metabolaid® app combines consumer appreciation of the product, changes in lifestyle habits and digital tracking, giving the users a personalized, exclusive connection with the product, and ultimately a more thorough control over their overall health.