Monteloeder has been awarded by the USP (United States Pharmacopeia) for contributing in its “Donor Recognition Program” in the development of USP Monographs for Dietary Supplements and in the manufacture of Primary Reference Standards.
Melatonin, in addition to its presence in vertebrates, has also been found in bacteria, unicellular organisms, fungi and plants. According to the antioxidant properties described, it is considered that the consumption of plants rich in melatonin can help prevent oxidative stress.
The knowledge of its biology can contribute to propose pharmacological measures to stimulate its endogenous secretion through nutritional habits and aspects of lifestyle.
There is no elixir of eternal youth, but nowadays if there is a substance that approaches, that is melatonin.
The Nutraceutical sector is increasingly mature and the Quality Control of the ingredients is more demanding. For this reason, the sector should think about the use of the Primary Reference Standards for the quantification of actives in botanical extracts.
The nutraceutical and functional food industries are subject to regulations that establish the adequate microbiological criteria (EU Regulations 2073/2005 and 1441/2007) of food quality and safety, which refer to international standards developed in the ISO and CEN Committees.
Sixty years ago, the pharmaceutical industry focused on developing new active ingredients that involved long processes lasting at least ten years and costing millions, in which approximately five years would be spent on developing a new product that then required another five years for the approved clinical trials.
Botanical extracts contain many substances from the plant, among them main actives, which are the ones that give the extract functionality, and other substances that sometimes have synergistic activity.